Evaluating Mosquitoes for Insecticide Resistance
Centers for Disease Control and Prevention
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 Strategies for Resistance Management


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 (Glossary Explained)This term is defined in the glossary.

Strategies for Resistance Management

  • Resistance surveillance should be conducted in association with surveillance for control efficacy. Otherwise, the significance of changes in susceptibility cannot be determined.
  • The initial step in resistance surveillance is to establish a baseline for susceptibility in the mosquito population. The population need not be fully susceptible to establish this initial benchmark. Subsequent surveillance is for the purpose of detecting changes in the resistance level of the population.
  • A correlation between changes in control efficacy and resistance profile should be observed before resistance is considered to be the reason for the control failure. Control failure can result from many factors other than resistance.
  • Once an increase in resistance level is observed that correlates with a decline in control efficacy, the mechanism of the resistance should be determined. Some mechanisms affect efficacy of other insecticides or even other insecticide classes through cross-resistance. Some resistance mechanisms allow greater choice of alternative strategies than others.
  • The resistance problem should be mapped spatially. Most resistance problems are highly focalized and may be of significance to control in only a restricted area of a program's region of responsibility.
  • Choices at this point include:
    1. Continuing with the current compound until an unacceptable level of control is obtained
    2. Switching to an insecticide that is unaffected by the resistance,
    3. Relying more on breeding source reduction
    4. Using focal spraying to reduce selection for resistance in the larger mosquito population
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This page last reviewed July 3, 2001

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